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Moderate caloric restriction (15-20% below maintenance) supports AOD-9604 protocols without triggering metabolic adaptation or excessive muscle loss

If fever, chills, or other unexpected systemic reactions occur during an injection, it is likely due to the drug being delivered or possible contamination, rather than the bacteriostatic water itself

As with all research compounds, investigators should implement appropriate laboratory safety protocols and follow institutional guidelines for handling investigational chemical compounds in controlled research environments

Another approach that would also not address the classical antimicrobial function is the use of cytotoxic activity

10.1002/mnfr.202300414 Mol

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